Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...
المؤلفون الرئيسيون: | Groselj, B, Kerr, M, Kiltie, A |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2013
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مواد مشابهة
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Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
حسب: Groselj, B, وآخرون
منشور في: (2013) -
The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer
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The HDAC Inhibitor Panobinostat Promotes Expression of Delta 133p53 Variants in TP53 Wild-type Bladder Cancer Cells
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Differential Roles of Ku70 and Ku80 in the MMEJ Phenotype
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Histone deacetylase inhibitors as radiosensitisers: Effects on DNA damage signalling and repair
حسب: Groselj, B, وآخرون
منشور في: (2013)