Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...
Հիմնական հեղինակներ: | Groselj, B, Kerr, M, Kiltie, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2013
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Նմանատիպ նյութեր
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Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
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Histone deacetylase inhibitors as radiosensitisers: Effects on DNA damage signalling and repair
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