Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.

BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...

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Main Authors: Groselj, B, Kerr, M, Kiltie, A
格式: Journal article
语言:English
出版: 2013