Incorporating local Ca2+ dynamics into single cell ventricular models

Incorporating local Ca2+ dynamics into single cell ventricular models

Understanding physiological mechanisms underlying the activity of the heart is of great medical importance. Mathematical modeling and numerical simulation have become a widely accepted method of unraveling the underlying mechanism of the heart. Calcium (Ca2∈+∈) dynamics regulate the excitation-contr...

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Bibliografiske detaljer
Main Authors:	Sher, A, Abramson, D, Enticott, C, Garic, S, Gavaghan, D, Noble, D, Noble, P, Peachey, T
Format:	Journal article
Sprog:	English
Udgivet:	2008

Lignende værker

The role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes.
af: Sher, A, et al.
Udgivet: (2008)

role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes
af: Sher, A, et al.
Udgivet: (2015)

Incorporating local Ca2+ dynamics into single cell ventricular models
Udgivet: (2008)

global sensitivity tool for cardiac cell modeling: Application to ionic current balance and hypertrophic signaling
af: Sher, A, et al.
Udgivet: (2010)

A global sensitivity tool for cardiac cell modeling: Application to ionic current balance and hypertrophic signaling.
af: Sher, A, et al.
Udgivet: (2010)

A global sensitivity tool for cardiac cell modeling: Application to ionic current balance and hypertrophic signaling.
af: Sher, A, et al.
Udgivet: (2010)

Functional significance of Na+/Ca2+ exchangers co-localization with ryanodine receptors.
af: Sher, A, et al.
Udgivet: (2007)

Multistability property in cardiac ionic models of mammalian and human ventricular cells
af: Surovyatkina, E, et al.
Udgivet: (2010)

Multistability property in cardiac ionic models of mammalian and human ventricular cells.
af: Surovyatkina, E, et al.
Udgivet: (2010)

Remodelling of calcium dynamics in guinea-pig ventricular cells
af: Noble, P, et al.
Udgivet: (2001)

Global Sensitivity Analysis of Arrhythmic Risk Biomarkers in Cardiac Single Cell Models
af: Sher, A, et al.
Udgivet: (2012)

High−throughput cardiac science on the Grid
af: Abramson, D, et al.
Udgivet: (2010)

Grid Computing Simulations of Ion Channel Block Effects on the ECG Using 3D Anatomically−Based Models
af: Gavaghan D Bernabeu MO Corrias A Pitt−Francis J Rodriguez B Bethwaite B Enticott C Garic S Peachey T Tan J Abramson D
Udgivet: (2009)

THE L-TYPE CALCIUM CHANNELS AND CALCIUM REGULATION IN VENTRICULAR MYOCYTES: IN SILICO STUDIES
af: Sher, A, et al.
Udgivet: (2009)

L−TYPE CALCIUM CHANNELS AND CALCIUM REGULATION IN VENTRICULAR MYOCYTES: IN SILICO STUDIES
af: Sher, A, et al.
Udgivet: (2009)

Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange.
af: Noble, D, et al.
Udgivet: (2007)

Modelling of Ca2+-activated chloride current in tracheal smooth muscle cells.
af: Roux, E, et al.
Udgivet: (2001)

Grid computing simulations of ion channel block effects on the ECG using 3D anatomically−based models
af: Bernabeu, M, et al.
Udgivet: (2009)

A model for simulating action potential in ventricular cell
af: Sabzpoushan, S, et al.
Udgivet: (2008)

A model for human ventricular tissue.
af: ten Tusscher, K, et al.
Udgivet: (2004)

A model for human ventricular tissue
af: Ten Tusscher, K, et al.
Udgivet: (2004)

A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling
af: Sher, A, et al.
Udgivet: (2013)

A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to Cardiac Ionic Channel Modelling
af: Sher, A, et al.
Udgivet: (2013)

A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling
af: Sher, A, et al.
Udgivet: (2013)

Ca2+-induced delayed afterdepolarizations are triggered by dyadic subspace Ca2+ affirming that increasing SERCA reduces aftercontractions
af: Fink, M, et al.
Udgivet: (2011)

Ca²⁺-induced delayed afterdepolarizations are triggered by dyadic subspace Ca2²⁺ affirming that increasing SERCA reduces aftercontractions.
af: Fink, M, et al.
Udgivet: (2011)

A survey on linear relations between main electrical components during action potential in ventricular cell
af: Sabzpoushan, S, et al.
Udgivet: (2007)

Incorporation of cellular models of arrythmia into multidimensional cardiac models
af: Bradley, C, et al.
Udgivet: (2000)

Models of cardiac ventricular action potentials: iterative interaction between experiment and simulation
af: Noble, D, et al.
Udgivet: (2001)

Regional acidosis locally inhibits but remotely stimulates Ca2+ waves in ventricular myocytes.
af: Ford, K, et al.
Udgivet: (2017)

Influence of Na/Ca exchange stoichiometry on model cardiac action potentials.
af: Noble, D
Udgivet: (2002)

Leveraging e-Science infrastructure for electrochemical research.
af: Peachey, T, et al.
Udgivet: (2011)

Simulation of Na/Ca exchange activity during ischemia.
af: Noble, D
Udgivet: (2002)

Direct optical mapping signal synthesis over a geometrically accurate ventricular model
af: Bishop, M, et al.
Udgivet: (2005)

A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to L−type Calcium Channel Modelling
af: Sher, A, et al.
Udgivet: (2010)

Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study.
af: Iribe, G, et al.
Udgivet: (2006)

Modeling of molecular and cellular mechanisms involved in Ca2+ signal encoding in airway myocytes.
af: Marhl, M, et al.
Udgivet: (2006)

Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low.
af: Swietach, P, et al.
Udgivet: (2008)

Contributions of inwardly rectifying K+ currents to repolarization assessed using mathematical models of human ventricular myocytes.
af: Fink, M, et al.
Udgivet: (2006)

Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate.
af: Iribe, G, et al.
Udgivet: (2009)