Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant.

Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant.

Constrained binding peptides (peptide aptamers) may serve as tools to explore protein conformations and disrupt protein-protein interactions. The quality of the protein scaffold, by which the binding peptide is constrained and presented, is of crucial importance. SQT (Stefin A Quadruple Mutant-Tracy...

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Hlavní autoři: Stadler, L, Hoffmann, T, Tomlinson, D, Song, Q, Lee, T, Busby, M, Nyathi, Y, Gendra, E, Tiede, C, Flanagan, K, Cockell, S, Wipat, A, Harwood, C, Wagner, S, Knowles, M, Davis, J, Keegan, N, Ferrigno, P
Médium: Journal article
Jazyk:English
Vydáno: 2011

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