Electrochemical detection of glutathione: An electrochemically initiated reaction pathway

The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a...

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Κύριοι συγγραφείς: Seymour, E, Wilkins, S, Lawrence, N, Compton, R
Μορφή: Journal article
Έκδοση: 2002
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author Seymour, E
Wilkins, S
Lawrence, N
Compton, R
author_facet Seymour, E
Wilkins, S
Lawrence, N
Compton, R
author_sort Seymour, E
collection OXFORD
description The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1-80 μM for glutathione with a corresponding limit of detection of 0.94 μM. The efficacy of the approach has been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 μM glutathione in a growth tissue media containing a number of important biomarkers.
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spelling oxford-uuid:d2f8ce2b-0fbf-4286-8e61-8be6467e70b12022-03-27T08:07:59ZElectrochemical detection of glutathione: An electrochemically initiated reaction pathwayJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d2f8ce2b-0fbf-4286-8e61-8be6467e70b1Symplectic Elements at Oxford2002Seymour, EWilkins, SLawrence, NCompton, RThe electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1-80 μM for glutathione with a corresponding limit of detection of 0.94 μM. The efficacy of the approach has been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 μM glutathione in a growth tissue media containing a number of important biomarkers.
spellingShingle Seymour, E
Wilkins, S
Lawrence, N
Compton, R
Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title_full Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title_fullStr Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title_full_unstemmed Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title_short Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
title_sort electrochemical detection of glutathione an electrochemically initiated reaction pathway
work_keys_str_mv AT seymoure electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway
AT wilkinss electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway
AT lawrencen electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway
AT comptonr electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway