Electrochemical detection of glutathione: An electrochemically initiated reaction pathway
The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a...
| Main Authors: | , , , |
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| Format: | Journal article |
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2002
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| _version_ | 1826298324632731648 |
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| author | Seymour, E Wilkins, S Lawrence, N Compton, R |
| author_facet | Seymour, E Wilkins, S Lawrence, N Compton, R |
| author_sort | Seymour, E |
| collection | OXFORD |
| description | The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1-80 μM for glutathione with a corresponding limit of detection of 0.94 μM. The efficacy of the approach has been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 μM glutathione in a growth tissue media containing a number of important biomarkers. |
| first_indexed | 2024-03-07T04:45:05Z |
| format | Journal article |
| id | oxford-uuid:d2f8ce2b-0fbf-4286-8e61-8be6467e70b1 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T04:45:05Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:d2f8ce2b-0fbf-4286-8e61-8be6467e70b12022-03-27T08:07:59ZElectrochemical detection of glutathione: An electrochemically initiated reaction pathwayJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d2f8ce2b-0fbf-4286-8e61-8be6467e70b1Symplectic Elements at Oxford2002Seymour, EWilkins, SLawrence, NCompton, RThe electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1-80 μM for glutathione with a corresponding limit of detection of 0.94 μM. The efficacy of the approach has been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 μM glutathione in a growth tissue media containing a number of important biomarkers. |
| spellingShingle | Seymour, E Wilkins, S Lawrence, N Compton, R Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title | Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title_full | Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title_fullStr | Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title_full_unstemmed | Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title_short | Electrochemical detection of glutathione: An electrochemically initiated reaction pathway |
| title_sort | electrochemical detection of glutathione an electrochemically initiated reaction pathway |
| work_keys_str_mv | AT seymoure electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway AT wilkinss electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway AT lawrencen electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway AT comptonr electrochemicaldetectionofglutathioneanelectrochemicallyinitiatedreactionpathway |