Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
Parkinson’s disease (PD) is characterized by a progressive deterioration of motor and cognitive functions. Although death of dopamine neurons is the hallmark pathology of PD, this is a late-stage disease process preceded by neuronal dysfunction. Here we describe early physiological perturbations in...
প্রধান লেখক: | Beccano-Kelly, DA, Cherubini, M, Mousba, Y, Cramb, KML, Giussani, S, Caiazza, MC, Rai, P, Vingill, S, Bengoa-Vergniory, N, Ng, B, Corda, G, Banerjee, A, Vowles, J, Cowley, S, Wade-Martins, R |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
Cell Press
2023
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অনুরূপ উপাদানগুলি
অনুরূপ উপাদানগুলি
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Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
অনুযায়ী: Dayne A. Beccano-Kelly, অন্যান্য
প্রকাশিত: (2023-07-01) -
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
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MAPT genetic variation and neuronal maturity alter isoform expression affecting axonal transport in iPSC-derived dopamine neurons.
অনুযায়ী: Beevers, J, অন্যান্য
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Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
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MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons
অনুযায়ী: Joel E. Beevers, অন্যান্য
প্রকাশিত: (2017-08-01)