Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling

Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling

Bibliografski detalji
Glavni autori:	Khoo, J, Bursill, C, Alp, N, McAteer, M, Channon, K
Format:	Conference item
Izdano:	2005

Slični predmeti

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
od: Alp, N, i dr.
Izdano: (2004)

Tetrahydrobiopterin deficiency uncouples nitric oxide synthase and causes pulmonary hypertension
od: Khoo, J, i dr.
Izdano: (2004)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
od: Crabtree, M, i dr.
Izdano: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
od: Crabtree, M, i dr.
Izdano: (2011)

Tetrahydrobiopterin Prevents Lung Ischemia/reperfusion-Induced Uncoupling of Endothelial Nitric Oxide Synthase
od: Juni, R, i dr.
Izdano: (2012)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
od: Alp, N, i dr.
Izdano: (2004)

Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
od: Crabtree, M, i dr.
Izdano: (2013)

Tetrahydrobiopterin deficiency increases susceptibility to atherosclerosis
od: Khoo, J, i dr.
Izdano: (2005)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
od: Cai, S, i dr.
Izdano: (2005)

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
od: Channon, K
Izdano: (2004)

Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation
od: Cai, S, i dr.
Izdano: (2004)

Tetrahydrobiopterin and nitric oxide synthase recouplers
od: Channon, KM
Izdano: (2020)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
od: Alp, N, i dr.
Izdano: (2003)

Prevention of hypoxia-induced pulmonary hypertension and vascular remodelling by targeting endothelial tetrahydrobiopterin-dependent nitric oxide synthase regulation
od: Khoo, J, i dr.
Izdano: (2005)

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
od: Alp, N, i dr.
Izdano: (2004)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
od: Alp, N, i dr.
Izdano: (2003)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
od: Cai, S, i dr.
Izdano: (2002)

Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
od: Crabtree, M, i dr.
Izdano: (2009)

Endothelial tetrahydrobiopterin regulates eNOS coupling/uncoupling independent of vascular disease: Insights from targeted transgenic models
od: Bendall, J, i dr.
Izdano: (2004)

Increased GTP-cyclohydrolase I expression but not vitamin C treatment restored accelerated atherosclerotic lesion formation in apolipoprotein E-deficient mice overexpressing endothelial nitric oxide synthase
od: Takaya, T, i dr.
Izdano: (2004)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
od: Alp, N, i dr.
Izdano: (2003)

Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling.
od: Alkaitis, MS, i dr.
Izdano: (2012)

Recoupling the cardiac nitric oxide synthases: Tetrahydrobiopterin synthesis and recycling
od: Alkaitis, MS, i dr.
Izdano: (2012)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
od: Cai, S, i dr.
Izdano: (2004)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
od: Cai, S, i dr.
Izdano: (2004)

Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells.
od: McDonald, D, i dr.
Izdano: (2004)

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.
od: Khoo, J, i dr.
Izdano: (2005)

Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis.
od: Antoniades, C, i dr.
Izdano: (2009)

CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis.
od: Ali, Z, i dr.
Izdano: (2008)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
od: Alp, N, i dr.
Izdano: (2003)

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
od: Antoniades, C, i dr.
Izdano: (2006)

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
od: Antoniades, C, i dr.
Izdano: (2011)

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling
od: Antoniades, C, i dr.
Izdano: (2011)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling.
od: Hashimoto, T, i dr.
Izdano: (2016)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling
od: Hashimoto, T, i dr.
Izdano: (2016)

Statin treatment improves vascular redox state through a tetrahydrobiopterin-mediated re-coupling of endothelial nitric oxide synthase, in human atherosclerosis
od: Antoniades, C, i dr.
Izdano: (2011)

Increased endothelial tetrahydrobiopterin levels in GTPCH-transgenic mice
od: Alp, N, i dr.
Izdano: (2002)

Letter by Antoniades et al regarding article, "Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction".
od: Antoniades, C, i dr.
Izdano: (2010)

Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.
od: Khoo, J, i dr.
Izdano: (2004)

Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
od: Chuaiphichai, S, i dr.
Izdano: (2023)