Systematic identification of structure-specific protein–protein interactions

Systematic identification of structure-specific protein–protein interactions

The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of proteins could help understand disease mechanisms, but current methods do not pinpoint structure-specifi...

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Main Authors: Holfeld, A, Schuster, D, Sesterhenn, F, Gillingham, AK, Stalder, P, Haenseler, W, Barrio-Hernandez, I, Ghosh, D, Vowles, J, Cowley, SA, Nagel, L, Khanppnavar, B, Serdiuk, T, Beltrao, P, Korkhov, VM, Munro, S, Riek, R, de Souza, N, Picotti, P
Format: Journal article
Language:English
Published: Springer 2024

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