The use of colour vision measurement in the diagnosis of digoxin toxicity.

Colour vision has been measured, using the Farnsworth-Munsell 100-Hue test, in control subjects and in patients taking digoxin. In 10 patients with digitalis toxicity, of whom only two described symptomatic abnormalities, colour vision was impaired compared with that of both control subjects and non...

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Main Authors: Aronson, J, Ford, A
Format: Journal article
Language:English
Published: 1980
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author Aronson, J
Ford, A
author_facet Aronson, J
Ford, A
author_sort Aronson, J
collection OXFORD
description Colour vision has been measured, using the Farnsworth-Munsell 100-Hue test, in control subjects and in patients taking digoxin. In 10 patients with digitalis toxicity, of whom only two described symptomatic abnormalities, colour vision was impaired compared with that of both control subjects and non-toxic patients who had been taking digoxin for more than two months. Withdrawal of digoxin from toxic patients led to improved colour vision. Colour vision scores correlated well with (a) log plasma digoxin concentrations, and (b) various measures of the pharmacodynamic effects of cardiac glycosides on cation transport in the patients' own erythrocytes. These results suggest that colour vision assessment may be of use in screening for digitalis toxicity at the bedside and in assessing the degree of digitalis intoxication in an individual patient as an aid to clinical research.
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spelling oxford-uuid:d30af9c4-f634-45a9-bb52-1b37099955e42022-03-27T08:08:31ZThe use of colour vision measurement in the diagnosis of digoxin toxicity.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d30af9c4-f634-45a9-bb52-1b37099955e4EnglishSymplectic Elements at Oxford1980Aronson, JFord, AColour vision has been measured, using the Farnsworth-Munsell 100-Hue test, in control subjects and in patients taking digoxin. In 10 patients with digitalis toxicity, of whom only two described symptomatic abnormalities, colour vision was impaired compared with that of both control subjects and non-toxic patients who had been taking digoxin for more than two months. Withdrawal of digoxin from toxic patients led to improved colour vision. Colour vision scores correlated well with (a) log plasma digoxin concentrations, and (b) various measures of the pharmacodynamic effects of cardiac glycosides on cation transport in the patients' own erythrocytes. These results suggest that colour vision assessment may be of use in screening for digitalis toxicity at the bedside and in assessing the degree of digitalis intoxication in an individual patient as an aid to clinical research.
spellingShingle Aronson, J
Ford, A
The use of colour vision measurement in the diagnosis of digoxin toxicity.
title The use of colour vision measurement in the diagnosis of digoxin toxicity.
title_full The use of colour vision measurement in the diagnosis of digoxin toxicity.
title_fullStr The use of colour vision measurement in the diagnosis of digoxin toxicity.
title_full_unstemmed The use of colour vision measurement in the diagnosis of digoxin toxicity.
title_short The use of colour vision measurement in the diagnosis of digoxin toxicity.
title_sort use of colour vision measurement in the diagnosis of digoxin toxicity
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