Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry.
Pharmaceutical counterfeiting has become a significant public health problem worldwide and new, rapid, user-friendly, reliable and inexpensive methods for drug quality screening are needed. This work illustrates the chemical characterization of genuine and fake artesunate antimalarial tablets by por...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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| _version_ | 1797096723690029056 |
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| author | Ricci, C Nyadong, L Yang, F Fernandez, F Brown, C Newton, P Kazarian, S |
| author_facet | Ricci, C Nyadong, L Yang, F Fernandez, F Brown, C Newton, P Kazarian, S |
| author_sort | Ricci, C |
| collection | OXFORD |
| description | Pharmaceutical counterfeiting has become a significant public health problem worldwide and new, rapid, user-friendly, reliable and inexpensive methods for drug quality screening are needed. This work illustrates the chemical characterization of genuine and fake artesunate antimalarial tablets by portable Raman spectroscopy and validation by FT-Raman spectroscopy and ambient mass spectrometry. The applicability of a compact and robust portable Raman spectrometer (TruScan) for the in situ chemical identification of counterfeit tablets is reported. |
| first_indexed | 2024-03-07T04:45:37Z |
| format | Journal article |
| id | oxford-uuid:d3271be9-d599-403a-9dcb-59151865085f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:45:37Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:d3271be9-d599-403a-9dcb-59151865085f2022-03-27T08:09:25ZAssessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d3271be9-d599-403a-9dcb-59151865085fEnglishSymplectic Elements at Oxford2008Ricci, CNyadong, LYang, FFernandez, FBrown, CNewton, PKazarian, SPharmaceutical counterfeiting has become a significant public health problem worldwide and new, rapid, user-friendly, reliable and inexpensive methods for drug quality screening are needed. This work illustrates the chemical characterization of genuine and fake artesunate antimalarial tablets by portable Raman spectroscopy and validation by FT-Raman spectroscopy and ambient mass spectrometry. The applicability of a compact and robust portable Raman spectrometer (TruScan) for the in situ chemical identification of counterfeit tablets is reported. |
| spellingShingle | Ricci, C Nyadong, L Yang, F Fernandez, F Brown, C Newton, P Kazarian, S Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title | Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title_full | Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title_fullStr | Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title_full_unstemmed | Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title_short | Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry. |
| title_sort | assessment of hand held raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by ft raman spectroscopy and direct ionization mass spectrometry |
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