Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Diğer sürümleri göster (2)

Nicastrin (NCSTN) is a component of the γ-secretase complex and therefore potentially a candidate risk gene for Alzheimer's disease. Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. DNA recombination was used to...

Detaylı Bibliyografya
Asıl Yazarlar:	Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2012

Benzer Materyaller

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
Yazar:: Hamilton, G, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus
Yazar:: Hamilton, G, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Haplotype-specific expression of exon 10 at the human MAPT locus
Yazar:: Caffrey, T, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Haplotype-specific expression of exon 10 at the human MAPT locus.
Yazar:: Caffrey, T, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus.
Yazar:: Caffrey, T, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Functional MAPT haplotypes: bridging the gap between genotype and neuropathology.
Yazar:: Caffrey, T, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Haplotypic analysis of the TNF locus by association efficiency and entropy.
Yazar:: Ackerman, H, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Haplotypic analysis of the TNF locus by association efficiency and entropy
Yazar:: Ackerman, H, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Bayesian quantitative trait locus mapping using inferred haplotypes.
Yazar:: Durrant, C, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Genetics: The MAPT locus-a genetic paradigm in disease susceptibility.
Yazar:: Wade-Martins, R
Baskı/Yayın Bilgisi: (2012)

Haplotype mapping of the bronchiolitis susceptibility locus near IL8.
Yazar:: Hull, J, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Studies at the hemochromatosis (HFE) locus : gene conversions, haplotypes, and association analysis
Yazar:: Kamihara-Ting, Junne
Baskı/Yayın Bilgisi: (2008)

DNA polymorphism, haplotype structure and balancing selection in the Leavenworthia PgiC locus.
Yazar:: Filatov, D, ve diğerleri
Baskı/Yayın Bilgisi: (1999)

Expression of the KIAA0319 gene from a haplotype associated with developmental dyslexia
Yazar:: Dennis, M, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Familial Alzheimer's disease coding mutations reduce Presenilin-1 expression in a novel genomic locus reporter model.
Yazar:: Ahmadi, S, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.
Yazar:: Chao, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium
Yazar:: Chao, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Unusual haplotypic structure of IL8, a susceptibility locus for a common respiratory virus.
Yazar:: Hull, J, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Haplotypic relationship between SNP and microsatellite markers at the NOS2A locus in two populations.
Yazar:: Burgner, D, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

HLA class-I and class-II allele frequencies and two-locus haplotypes in Melanesians of Vanuatu and New Caledonia.
Yazar:: Maitland, K, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
Yazar:: Bell, C, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Accuracy of haplotype reconstruction from haplotype-tagging single-nucleotide polymorphisms
Yazar:: Forton, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Accuracy of haplotype reconstruction from haplotype-tagging single-nucleotide polymorphisms.
Yazar:: Forton, J, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells.
Yazar:: Wade-Martins, R, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders
Yazar:: Lai, M, ve diğerleri
Baskı/Yayın Bilgisi: (2017)

HLA haplotype associations with disease.
Yazar:: Thomson, G, ve diğerleri
Baskı/Yayın Bilgisi: (1979)

A haplotype map for the laboratory mouse.
Yazar:: Mott, R
Baskı/Yayın Bilgisi: (2007)

Haplotype studies in Wilson disease.
Yazar:: Thomas, G, ve diğerleri
Baskı/Yayın Bilgisi: (1994)

Efficient haplotyping for families
Yazar:: Williams, Amy Lynne, Ph.D. Massachusetts Institute of Technology
Baskı/Yayın Bilgisi: (2010)

An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.
Yazar:: Jaeger, E, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Haplotype tagging for the identification of common disease genes.
Yazar:: Johnson, G, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection.
Yazar:: Hibbitt, O, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Haplotype structure and selection of the MDM2 oncogene in humans.
Yazar:: Atwal, G, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Absence of relationship between MTTP haplotypes and longevity.
Yazar:: Neville, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Dissection of the multiple sclerosis associated DR2 haplotype.
Yazar:: Etzensperger, R, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

HAPLOTYPES IN WILSON DISEASE - IMPLICATIONS FOR MUTATIONAL ANALYSIS
Yazar:: Thomas, G, ve diğerleri
Baskı/Yayın Bilgisi: (1993)

Infectious delivery and expression of a 135 kb human FRDA genomic DNA locus complements Friedreich's ataxia deficiency in human cells.
Yazar:: Gomez-Sebastian, S, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Screening for recently selected alleles by analysis of human haplotype similarity.
Yazar:: Hanchard, N, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Inference of population structure using dense haplotype data.
Yazar:: Lawson, D, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Reply to Reeves et al.: No evidence for rare ERAP1 haplotypes and haplotype combinations in ankylosing spondylitis
Yazar:: Wordsworth, B, ve diğerleri
Baskı/Yayın Bilgisi: (2017)