Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

عرض إصدارات أخرى (2)

Nicastrin (NCSTN) is a component of the γ-secretase complex and therefore potentially a candidate risk gene for Alzheimer's disease. Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. DNA recombination was used to...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R
التنسيق:	Journal article
اللغة:	English
منشور في:	2012

مواد مشابهة

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
حسب: Hamilton, G, وآخرون
منشور في: (2012)

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus
حسب: Hamilton, G, وآخرون
منشور في: (2012)

Haplotype-specific expression of exon 10 at the human MAPT locus
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Haplotype-specific expression of exon 10 at the human MAPT locus.
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An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.
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منشور في: (1991)

Variants and haplotypes of the angiotensinogen gene are associated with hypertension in the Caerphilly Prospective Study
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Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders
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