Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Taispeáin leaganacha eile (2)

Nicastrin (NCSTN) is a component of the γ-secretase complex and therefore potentially a candidate risk gene for Alzheimer's disease. Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. DNA recombination was used to...

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Príomhchruthaitheoirí:	Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2012

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