Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
Nicastrin (NCSTN) is a component of the γ-secretase complex and therefore potentially a candidate risk gene for Alzheimer's disease. Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. DNA recombination was used to...
मुख्य लेखकों: | Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2012
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समान संसाधन
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Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
द्वारा: Hamilton, G, और अन्य
प्रकाशित: (2012) -
Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus
द्वारा: Hamilton, G, और अन्य
प्रकाशित: (2012) -
Haplotype-specific expression of exon 10 at the human MAPT locus
द्वारा: Caffrey, T, और अन्य
प्रकाशित: (2006) -
Haplotype-specific expression of exon 10 at the human MAPT locus.
द्वारा: Caffrey, T, और अन्य
प्रकाशित: (2006) -
Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus.
द्वारा: Caffrey, T, और अन्य
प्रकाशित: (2008)