Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Nicastrin (NCSTN) is a component of the γ-secretase complex and therefore potentially a candidate risk gene for Alzheimer's disease. Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. DNA recombination was used to...

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主要な著者:	Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R
フォーマット:	Journal article
言語:	English
出版事項:	2012

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. 著者: Hamilton, G, Killick, R, Lambert, J, Amouyel, P, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

出版事項 2012

Journal article

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus 著者: Hamilton, G, Killick, R, Lambert, J, Amouyel, P, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

出版事項 2012

Journal article

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. 著者: Hamilton, G, Killick, R, Lambert, J, Amouyel, P, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus 著者: Hamilton, G, Killick, R, Lambert, J, Amouyel, P, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

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