Appearance of a single amino acid insertion at position 33 in HIV type 1 protease under a lopinavir-containing regimen, associated with reduced protease inhibitor susceptibility.

HIV drug resistance is a multifactorial phenomenon and constitutes a major concern as it results in therapy failure. The aim of this study was to assess the impact of an amino acid insertion identified at position 33 of the protease gene, derived from samples from three patients under lopinavir ther...

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Bibliographic Details
Main Authors: Magiorkinis, E, Paraskevis, D, Detsika, MG, Lu, L, Magiorkinis, G, Lazanas, M, Imbrechts, S, Van Laethem, K, Vandamme, A, Pilot-Matias, T, Molla, A, Camacho, R, Hatzakis, A
Format: Journal article
Language:English
Published: 2011