Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.

The insulin-like growth factor (IGF) type 1 receptor is required for growth, transformation, and protection from apoptosis. IGFs can enhance cell migration, which is known to be influenced via regulation of the E-cadherin/beta-catenin complex. We sought to investigate whether IGF-1 modulated the int...

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Bibliografiske detaljer
Main Authors:	Playford, M, Bicknell, D, Bodmer, W, Macaulay, V
Format:	Journal article
Sprog:	English
Udgivet:	2000

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