Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.

The insulin-like growth factor (IGF) type 1 receptor is required for growth, transformation, and protection from apoptosis. IGFs can enhance cell migration, which is known to be influenced via regulation of the E-cadherin/beta-catenin complex. We sought to investigate whether IGF-1 modulated the int...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Playford, M, Bicknell, D, Bodmer, W, Macaulay, V
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2000