Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems
<strong>Background<br></strong> COVID-19 vaccines are protective against disease. Pregnant women benefit from vaccination as they are at higher risk of poor maternal and neonatal outcomes following infection. <br><strong>Methods<br></strong> Following regula...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
SAGE Publications
2022
|
| _version_ | 1826310034542297088 |
|---|---|
| author | Richardson, JL Stephens, S Chappell, LC Campbell, H Amirthalingam, G O'Boyle, S Bukasa, A Knight, M Hodson, KK |
| author_facet | Richardson, JL Stephens, S Chappell, LC Campbell, H Amirthalingam, G O'Boyle, S Bukasa, A Knight, M Hodson, KK |
| author_sort | Richardson, JL |
| collection | OXFORD |
| description | <strong>Background<br></strong>
COVID-19 vaccines are protective against disease. Pregnant women benefit from vaccination as they are at higher risk of poor maternal and neonatal outcomes following infection.
<br><strong>Methods<br></strong>
Following regulatory approval of two COVID-19 vaccines in the United Kingdom, a rapid national study of vaccination in pregnancy was instituted using three existing safety surveillance platforms: UKOSS, UKTIS and VIP. This preliminary report describes the data collected up to the 15th June 2021.
<br><strong>Results<br></strong>
There were 971 reports of COVID-19 vaccination in the UKOSS/UKTIS (n = 493) and VIP (n = 478) monitoring systems describing 908 individual pregnancies. Pfizer-BioNTech mRNA vaccination was most common (n = 501, 55.2%), most women were vaccinated in their second or third trimester (n = 566, 62.3%), and were mainly vaccinated due to occupational infection risk (n = 577, 63.5%).
<br><strong>Conclusion<br></strong>
Obstetric outcome data will be obtained by December 2021. However, women should not delay vaccination whilst awaiting further safety data to emerge. |
| first_indexed | 2024-03-07T07:44:32Z |
| format | Journal article |
| id | oxford-uuid:d3664c41-5f91-4b9f-bcda-e400dbe2082e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:44:32Z |
| publishDate | 2022 |
| publisher | SAGE Publications |
| record_format | dspace |
| spelling | oxford-uuid:d3664c41-5f91-4b9f-bcda-e400dbe2082e2023-05-22T13:06:47ZMonitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systemsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d3664c41-5f91-4b9f-bcda-e400dbe2082eEnglishSymplectic ElementsSAGE Publications2022Richardson, JLStephens, SChappell, LCCampbell, HAmirthalingam, GO'Boyle, SBukasa, AKnight, MHodson, KK<strong>Background<br></strong> COVID-19 vaccines are protective against disease. Pregnant women benefit from vaccination as they are at higher risk of poor maternal and neonatal outcomes following infection. <br><strong>Methods<br></strong> Following regulatory approval of two COVID-19 vaccines in the United Kingdom, a rapid national study of vaccination in pregnancy was instituted using three existing safety surveillance platforms: UKOSS, UKTIS and VIP. This preliminary report describes the data collected up to the 15th June 2021. <br><strong>Results<br></strong> There were 971 reports of COVID-19 vaccination in the UKOSS/UKTIS (n = 493) and VIP (n = 478) monitoring systems describing 908 individual pregnancies. Pfizer-BioNTech mRNA vaccination was most common (n = 501, 55.2%), most women were vaccinated in their second or third trimester (n = 566, 62.3%), and were mainly vaccinated due to occupational infection risk (n = 577, 63.5%). <br><strong>Conclusion<br></strong> Obstetric outcome data will be obtained by December 2021. However, women should not delay vaccination whilst awaiting further safety data to emerge. |
| spellingShingle | Richardson, JL Stephens, S Chappell, LC Campbell, H Amirthalingam, G O'Boyle, S Bukasa, A Knight, M Hodson, KK Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title | Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title_full | Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title_fullStr | Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title_full_unstemmed | Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title_short | Monitoring the safety of COVID-19 vaccination in pregnancy in the UK: A national study using the UK Obstetric Surveillance System (UKOSS), UK Teratology Information Service (UKTIS) and Vaccination in Pregnancy (VIP) safety monitoring systems |
| title_sort | monitoring the safety of covid 19 vaccination in pregnancy in the uk a national study using the uk obstetric surveillance system ukoss uk teratology information service uktis and vaccination in pregnancy vip safety monitoring systems |
| work_keys_str_mv | AT richardsonjl monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT stephenss monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT chappelllc monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT campbellh monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT amirthalingamg monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT oboyles monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT bukasaa monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT knightm monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems AT hodsonkk monitoringthesafetyofcovid19vaccinationinpregnancyintheukanationalstudyusingtheukobstetricsurveillancesystemukossukteratologyinformationserviceuktisandvaccinationinpregnancyvipsafetymonitoringsystems |