Mitochondrial creatine kinase is critically necessary for normal myocardial high-energy phosphate metabolism.

Mitochondrial creatine kinase is critically necessary for normal myocardial high-energy phosphate metabolism.

The individual functional significance of the various creatine kinase (CK) isoenzymes for myocardial energy homeostasis is poorly understood. Whereas transgenic hearts lacking the M subunit of CK (M-CK) show unaltered cardiac energetics and left ventricular (LV) performance, deletion of M-CK in comb...

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Bibliographic Details
Main Authors:	Spindler, M, Niebler, R, Remkes, H, Horn, M, Lanz, T, Neubauer, S
Format:	Journal article
Language:	English
Published:	2002

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