Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

We present long-read Tet-assisted pyridine borane sequencing (lrTAPS) for targeted base-resolution sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb from nanogram-level input. Compatible with both Oxford Nanopore and PacBio Single-Molecule Real-Time (SMRT) sequencing, lrTAP...

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Bibliographic Details
Main Authors:	Liu, Y, Cheng, J, Siejka-Zielinska, P, Weldon, C, Roberts, H, Lopopolo, M, Magri, A, D'Arienzo, V, Harris, JM, McKeating, J, Song, C
Format:	Journal article
Published:	BMC 2020

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