Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis
Sepsis is a complex syndrome related to an infection-induced exaggerated inflammatory response, which is associated with a high mortality. Granzymes (Gzm) are proteases mainly found in cytotoxic lymphocytes that not only have a role in target cell death, but also as mediators of infection and inflam...
Main Authors: | García-Laorden, MI, Hoogendijk, AJ, Wiewel, MA, van Vught, LA, Schultz, MJ, Bovenschen, N, de Vos, AF, van der Poll, T |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2021
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