Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Smoking is a common risk factor for many diseases. We conducted genome-wide association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers (n = 31,266) and smoking initiation (n = 46,481) using samples from the ENGAGE Consortium. In a second stage, we tested selected SNPs wit...

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Asıl Yazarlar: Thorgeirsson, T, Gudbjartsson, D, Surakka, I, Vink, J, Amin, N, Geller, F, Sulem, P, Rafnar, T, Esko, T, Walter, S, Gieger, C, Rawal, R, Mangino, M, Prokopenko, I, Mägi, R, Keskitalo, K, Gudjonsdottir, I, Gretarsdottir, S, Stefansson, H, Thompson, JR, Aulchenko, Y, Nelis, M, Aben, K, den Heijer, M, Dirksen, A, Ashraf, H, Soranzo, N, Valdes, A, Steves, C, Uitterlinden, A, Hofman, A, Tönjes, A, Kovacs, P, Hottenga, J, Willemsen, G, Vogelzangs, N, Döring, A, Dahmen, N, Nitz, B, Pergadia, M, Saez, B, De Diego, V, Lezcano, V, Garcia-Prats, MD, Ripatti, S, Perola, M, Kettunen, J, Hartikainen, A, Pouta, A, Laitinen, J, Isohanni, M, Huei-Yi, S, Allen, M, Krestyaninova, M, Hall, A, Jones, G, van Rij, A, Mueller, T, Dieplinger, B, Haltmayer, M, Jonsson, S, Matthiasson, SE, Oskarsson, H, Tyrfingsson, T, Kiemeney, L, Mayordomo, J, Lindholt, J, Pedersen, J, Franklin, W, Wolf, H, Montgomery, G, Heath, A, Martin, N, Madden, P, Giegling, I, Rujescu, D, Järvelin, MR, Salomaa, V, Stumvoll, M, Spector, T, Wichmann, H, Metspalu, A, Samani, N, Penninx, B, Oostra, B, Boomsma, D, Tiemeier, H, van Duijn, C, Kaprio, J, Gulcher, JR, McCarthy, M, Peltonen, L, Thorsteinsdottir, U, Stefansson, K
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2010

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