Pitfalls in estimating piperaquine elimination.
By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in...
| Main Authors: | , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado: |
2005
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| _version_ | 1826298433676247040 |
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| author | Tarning, J Lindegårdh, N Annerberg, A Singtoroj, T Day, N Ashton, M White, N |
| author_facet | Tarning, J Lindegårdh, N Annerberg, A Singtoroj, T Day, N Ashton, M White, N |
| author_sort | Tarning, J |
| collection | OXFORD |
| description | By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs. |
| first_indexed | 2024-03-07T04:46:46Z |
| format | Journal article |
| id | oxford-uuid:d38fef1a-f5c7-42b9-bc5e-99abef55a3ae |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:46:46Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:d38fef1a-f5c7-42b9-bc5e-99abef55a3ae2022-03-27T08:12:09ZPitfalls in estimating piperaquine elimination.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d38fef1a-f5c7-42b9-bc5e-99abef55a3aeEnglishSymplectic Elements at Oxford2005Tarning, JLindegårdh, NAnnerberg, ASingtoroj, TDay, NAshton, MWhite, NBy using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs. |
| spellingShingle | Tarning, J Lindegårdh, N Annerberg, A Singtoroj, T Day, N Ashton, M White, N Pitfalls in estimating piperaquine elimination. |
| title | Pitfalls in estimating piperaquine elimination. |
| title_full | Pitfalls in estimating piperaquine elimination. |
| title_fullStr | Pitfalls in estimating piperaquine elimination. |
| title_full_unstemmed | Pitfalls in estimating piperaquine elimination. |
| title_short | Pitfalls in estimating piperaquine elimination. |
| title_sort | pitfalls in estimating piperaquine elimination |
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