Pitfalls in estimating piperaquine elimination.
By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in...
Κύριοι συγγραφείς: | Tarning, J, Lindegårdh, N, Annerberg, A, Singtoroj, T, Day, N, Ashton, M, White, N |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2005
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Development and validation of an automated solid phase extraction and liquid chromatographic method for the determination of piperaquine in urine.
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Pharmacokinetic evaluation and metabolite characterization of the antimalarial piperaquine in the rat
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Έκδοση: (2007) -
Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.
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Characterization of human urinary metabolites of the antimalarial piperaquine.
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Έκδοση: (2006) -
Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.
ανά: Tarning, J, κ.ά.
Έκδοση: (2014)