Chimeric human opsins as optogenetic light sensitisers

Human opsin-based photopigments have great potential as light-sensitisers, but their requirement for phototransduction cascade-specific second messenger proteins may restrict their functionality in non-native cell types. In this study, eight chimeric human opsins were generated consisting of a backb...

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Bibliographic Details
Main Authors: Hickey, D, Davies, W, Hughes, S, Rodgers, J, Thavanesan, N, Maclaren, R, Hankins, M
Format: Journal article
Language:English
Published: Company of Biologists 2021