Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis)

Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis)

BACKGROUND: Melioidosis, caused by infection with Burkholderia (B.) pseudomallei, is a severe illness that is endemic in Southeast Asia. Osteopontin (OPN) is a phosphorylated glycoprotein that is involved in several immune responses including induction of T-helper 1 cytokines and recruitment of inf...

Podrobná bibliografie
Hlavní autoři:	Van Der Windt, G, Wiersinga, W, Wieland, C, Tjia, I, Day, N, Peacock, S, Florquin, S, Van Der Poll, T
Médium:	Journal article
Jazyk:	English
Vydáno:	Public Library of Science 2010

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