A concise total synthesis of (+/-)-1-epiaustraline.

[reaction: see text] A concise total synthesis of 1-epiaustraline 3 is described that utilizes a diastereoselective Birch reduction of an electron-deficient pyrrole and a chelation-controlled vinyl Grignard addition to an aldehyde to introduce the C7 stereocenter. The C1 and C2 stereocenters were se...

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Detalles Bibliográficos
Main Authors: Donohoe, T, Sintim, H
Formato: Journal article
Idioma:English
Publicado: 2004