Spurious findings

It is well recognised that data will eventually “confess” if it is interrogated enough. Provided enough variables and tests are deployed, a “statistically significant” result can usually be obtained. Consequentially, many of the “discoveries” in clinical research later transpire to be spurious findi...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Cook, J, Ranstam, J
التنسيق: Journal article
منشور في: Wiley 2016
الوصف
الملخص:It is well recognised that data will eventually “confess” if it is interrogated enough. Provided enough variables and tests are deployed, a “statistically significant” result can usually be obtained. Consequentially, many of the “discoveries” in clinical research later transpire to be spurious findings reflecting only chance occurrences and the idiosyncrasies of the dataset and analysis strategies used, and do not reflect a real, let alone clinical useful, relationship.