Effective induction of HIV-specific CTL by multi-epitope using gene gun in a combined vaccination regime.

Reliable and effective induction of cytotoxic T-lymphocytes (CTL) is one of the prime objectives of vaccine research. Previously, novel HIV vaccine candidates were constructed as a string of CTL epitopes (20 human, 3 macaque and 1 mouse) delivered using a DNA vector [Hanke T, Schneider J, Gilbert SG...

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Bibliographic Details
Main Authors: Hanke, T, Neumann, VC, Blanchard, T, Sweeney, P, Hill, A, Smith, G, McMichael, A
Format: Journal article
Language:English
Published: 1999