Dynamic tuneable G protein-coupled receptor monomer-dimer populations

G protein-coupled receptors (GPCRs) are the largest class of membrane receptors, playing a key role in the regulation of processes as varied as neurotransmission and immune response. Evidence for GPCR oligomerisation has been accumulating that challenges the idea that GPCRs function solely as monome...

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Hlavní autoři: Dijkman, P, Castell, O, Goddard, A, Munoz-Garcia, J, de Graaf, C, Wallace, M, Watts, A
Médium: Journal article
Vydáno: Nature Publishing Group 2018