Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.

Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.

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A library of dimeric CD1d ligands, containing two α-galactosyl ceramide (α-GalCer) units linked by spacers of varying lengths has been synthesised. The key dimerisation reactions were carried out via copper-catalysed click reactions between a 6"-azido-6"-deoxy-α-galactosyl ceramide derivat...

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Bibliographic Details
Main Authors:	Jervis, P, Moulis, M, Jukes, J, Ghadbane, H, Cox, L, Cerundolo, V, Besra, G
Format:	Journal article
Language:	English
Published:	2012

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