Farnesyltransferase inhibitors.

The targeting of molecular abnormalities in neoplasms may provide an opportunity to improve the selectivity of cancer therapy. Ras mutations are a common genetic event in human cancers. Other genetic changes in tumors can signal through ras-dependent pathways as well. The targeting of ras through th...

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Bibliographic Details
Main Authors: Hahn, S, Bernhard, E, Mckenna, W
Format: Journal article
Language:English
Published: 2001