Why do peroxisomes associate with the cytoskeleton?

Attachment of peroxisomes to cytoskeleton and movement along microtubular filaments and actin cables are essential and highly regulated processes enabling metabolic efficiency, biogenesis, maintenance and inheritance of this dynamic cellular compartment. Several peroxisome-associated proteins have b...

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Main Authors: Neuhaus, A, Eggeling, C, Erdmann, R, Schliebs, W
Format: Journal article
Language:English
Published: Elsevier 2015
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author Neuhaus, A
Eggeling, C
Erdmann, R
Schliebs, W
author_facet Neuhaus, A
Eggeling, C
Erdmann, R
Schliebs, W
author_sort Neuhaus, A
collection OXFORD
description Attachment of peroxisomes to cytoskeleton and movement along microtubular filaments and actin cables are essential and highly regulated processes enabling metabolic efficiency, biogenesis, maintenance and inheritance of this dynamic cellular compartment. Several peroxisome-associated proteins have been identified, which mediate interaction with motor proteins, adaptor proteins or other constituents of the cytoskeleton. It appears that there is a species-specific complexity of protein-protein interactions required to control directional movement and arresting. An open question is why some proteins with a specific role in peroxisomal protein import have an additional function in the regulation of cytoskeleton binding and motility of peroxisomes. This article is part of a Special Issue entitled: Peroxisomes edited by Ralf Erdmann.
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spelling oxford-uuid:d4074d8d-708d-4d71-8754-4f68ad5c84e32022-03-27T08:15:28ZWhy do peroxisomes associate with the cytoskeleton?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d4074d8d-708d-4d71-8754-4f68ad5c84e3EnglishSymplectic Elements at OxfordElsevier2015Neuhaus, AEggeling, CErdmann, RSchliebs, WAttachment of peroxisomes to cytoskeleton and movement along microtubular filaments and actin cables are essential and highly regulated processes enabling metabolic efficiency, biogenesis, maintenance and inheritance of this dynamic cellular compartment. Several peroxisome-associated proteins have been identified, which mediate interaction with motor proteins, adaptor proteins or other constituents of the cytoskeleton. It appears that there is a species-specific complexity of protein-protein interactions required to control directional movement and arresting. An open question is why some proteins with a specific role in peroxisomal protein import have an additional function in the regulation of cytoskeleton binding and motility of peroxisomes. This article is part of a Special Issue entitled: Peroxisomes edited by Ralf Erdmann.
spellingShingle Neuhaus, A
Eggeling, C
Erdmann, R
Schliebs, W
Why do peroxisomes associate with the cytoskeleton?
title Why do peroxisomes associate with the cytoskeleton?
title_full Why do peroxisomes associate with the cytoskeleton?
title_fullStr Why do peroxisomes associate with the cytoskeleton?
title_full_unstemmed Why do peroxisomes associate with the cytoskeleton?
title_short Why do peroxisomes associate with the cytoskeleton?
title_sort why do peroxisomes associate with the cytoskeleton
work_keys_str_mv AT neuhausa whydoperoxisomesassociatewiththecytoskeleton
AT eggelingc whydoperoxisomesassociatewiththecytoskeleton
AT erdmannr whydoperoxisomesassociatewiththecytoskeleton
AT schliebsw whydoperoxisomesassociatewiththecytoskeleton