Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling.
The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved the crystal structure of the EphA4 ligand binding domain alone and in complex wi...
Egile Nagusiak: | , , , , , , , |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2009
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