Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling.

Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling.

The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved the crystal structure of the EphA4 ligand binding domain alone and in complex wi...

書誌詳細
主要な著者:	Bowden, T, Aricescu, A, Nettleship, J, Siebold, C, Rahman-Huq, N, Owens, R, Stuart, D, Jones, E
フォーマット:	Journal article
言語:	English
出版事項:	2009

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