Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.

Human ζ-crystallin is a Zn(2+)-lacking medium-chain dehydrogenase/reductase (MDR) included in the quinone oxidoreductase (QOR) family because of its activity with quinones. In the present work a novel enzymatic activity was characterized: the double bond α,β-hydrogenation of medium-chain 2-alkenals...

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Bibliographic Details
Main Authors: Porté, S, Moeini, A, Reche, I, Shafqat, N, Oppermann, U, Farrés, J, Parés, X
Format: Journal article
Language:English
Published: 2011