Towards extracellular vesicle based gene therapy for Huntington's disease
<p>Huntington's disease (HD) can be regarded as a model neurodegenerative disorder to screen potential genetic based therapeutics and their carriers. It is an autosomal dominant disorder caused by a mutation in a single gene that leads to progressive neurodegeneration caused in part by pr...
المؤلف الرئيسي: | O'Loughlin, A |
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مؤلفون آخرون: | Wood, M |
التنسيق: | أطروحة |
منشور في: |
2016
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الموضوعات: |
مواد مشابهة
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Real-time three-dimensional tracking of single vesicles reveals abnormal motion and pools of synaptic vesicles in neurons of Huntington's disease mice
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منشور في: (2021-10-01) -
DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease
حسب: Bhagyashree S. Joshi, وآخرون
منشور في: (2021-11-01) -
The Dichotomous Role of Extracellular Vesicles in the Central Nervous System
حسب: David R. Graykowski, وآخرون
منشور في: (2020-09-01) -
Presymptomatic targeted circuit manipulation for ameliorating Huntington’s disease pathogenesis
حسب: Ebenezer C. Ikefuama, وآخرون
منشور في: (2025-03-01) -
Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease
حسب: Zhichun Chen, وآخرون
منشور في: (2024-07-01)