Towards extracellular vesicle based gene therapy for Huntington's disease
<p>Huntington's disease (HD) can be regarded as a model neurodegenerative disorder to screen potential genetic based therapeutics and their carriers. It is an autosomal dominant disorder caused by a mutation in a single gene that leads to progressive neurodegeneration caused in part by pr...
Հիմնական հեղինակ: | O'Loughlin, A |
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Այլ հեղինակներ: | Wood, M |
Ձևաչափ: | Թեզիս |
Հրապարակվել է: |
2016
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Խորագրեր: |
Նմանատիպ նյութեր
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Real-time three-dimensional tracking of single vesicles reveals abnormal motion and pools of synaptic vesicles in neurons of Huntington's disease mice
: Sidong Chen, և այլն
Հրապարակվել է: (2021-10-01) -
DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease
: Bhagyashree S. Joshi, և այլն
Հրապարակվել է: (2021-11-01) -
The Dichotomous Role of Extracellular Vesicles in the Central Nervous System
: David R. Graykowski, և այլն
Հրապարակվել է: (2020-09-01) -
Presymptomatic targeted circuit manipulation for ameliorating Huntington’s disease pathogenesis
: Ebenezer C. Ikefuama, և այլն
Հրապարակվել է: (2025-03-01) -
Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease
: Zhichun Chen, և այլն
Հրապարակվել է: (2024-07-01)