Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades.

Recent evidence demonstrates that low-frequency oscillations of intracellular calcium on timescales of seconds to minutes drive distinct aspects of neuronal development, but the mechanisms by which these calcium transients are coupled to signaling cascades are not well understood. Here we test the h...

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Bibliographic Details
Main Authors: Dunn, T, Wang, C, Colicos, M, Zaccolo, M, DiPilato, L, Zhang, J, Tsien, R, Feller, M
Format: Journal article
Language:English
Published: 2006