Imaging of cAMP levels and protein kinase A activity reveals that retinal waves drive oscillations in second-messenger cascades.
Recent evidence demonstrates that low-frequency oscillations of intracellular calcium on timescales of seconds to minutes drive distinct aspects of neuronal development, but the mechanisms by which these calcium transients are coupled to signaling cascades are not well understood. Here we test the h...
Main Authors: | Dunn, T, Wang, C, Colicos, M, Zaccolo, M, DiPilato, L, Zhang, J, Tsien, R, Feller, M |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2006
|
Similar Items
-
cAMP: From long-range second messenger to nanodomain signalling
by: Musheshe, N, et al.
Published: (2017) -
Extracellular calcium and cAMP: second messengers as "third messengers"?
by: Hofer, A, et al.
Published: (2007) -
Restricted diffusion of a freely diffusible second messenger: Mechanisms underlying compartmentalized cAMP signalling
by: Zaccolo, M, et al.
Published: (2006) -
Restricted diffusion of a freely diffusible second messenger: mechanisms underlying compartmentalized cAMP signalling.
by: Zaccolo, M, et al.
Published: (2006) -
Microdomains of cAMP in heart cells
by: Zaccolo, M
Published: (2002)