Averaging of viral envelope glycoprotein spikes from electron cryotomography reconstructions using Jsubtomo.
Enveloped viruses utilize membrane glycoproteins on their surface to mediate entry into host cells. Three-dimensional structural analysis of these glycoprotein 'spikes' is often technically challenging but important for understanding viral pathogenesis and in drug design. Here, a protocol...
Hauptverfasser: | Huiskonen, J, Parsy, M, Li, S, Bitto, D, Renner, M, Bowden, T |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Journal of Visualized Experiments
2014
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