Averaging of viral envelope glycoprotein spikes from electron cryotomography reconstructions using Jsubtomo.
Enveloped viruses utilize membrane glycoproteins on their surface to mediate entry into host cells. Three-dimensional structural analysis of these glycoprotein 'spikes' is often technically challenging but important for understanding viral pathogenesis and in drug design. Here, a protocol...
| Autori principali: | , , , , , |
|---|---|
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
Journal of Visualized Experiments
2014
|