Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios
The mechanisms underlying hematopoietic lineage decisions remain disputed. Lineage affiliated transcription factors (TFs) with the capacity for lineage reprogramming, positive auto-regulation and mutual inhibition have been described to be expressed in uncommitted cell populations. This has led to t...
Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , , , , , , |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Nature Publishing Group
2016
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