Improved yield of a ligand-binding GPCR expressed in E. coli for structural studies.
The G-protein coupled receptor (GPCR), rat brain neurotensin receptor type I (NTS1) is one of a small number of GPCRs that have been successfully expressed in Escherichia coli as a functional, ligand-binding receptor, but yields of purified receptor are still low for comprehensive structural studies...
Main Authors: | Attrill, H, Harding, P, Smith, E, Ross, S, Watts, A |
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Format: | Journal article |
Language: | English |
Published: |
2009
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