Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics.
Among 384 patients with confirmed meningococcal disease, the likelihood of detecting Neisseria meningitidis DNA in cerebrospinal fluid (CSF) increased with age, serogroup B infection, and prehospitalization antibiotic treatment. Plasma and CSF genomic bacterial loads of non-B N. meningitidis serogro...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
2011
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| _version_ | 1826298621767712768 |
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| author | Darton, T Guiver, M Naylor, S Kaczmarski, E Borrow, R Read, R |
| author_facet | Darton, T Guiver, M Naylor, S Kaczmarski, E Borrow, R Read, R |
| author_sort | Darton, T |
| collection | OXFORD |
| description | Among 384 patients with confirmed meningococcal disease, the likelihood of detecting Neisseria meningitidis DNA in cerebrospinal fluid (CSF) increased with age, serogroup B infection, and prehospitalization antibiotic treatment. Plasma and CSF genomic bacterial loads of non-B N. meningitidis serogroups correlated significantly. Serogroup B-infected patients with genotype TNF2 (-308A) had significantly higher CSF bacterial loads. |
| first_indexed | 2024-03-07T04:49:39Z |
| format | Journal article |
| id | oxford-uuid:d484fca2-e55a-4a8f-a40e-3348e3fc29d4 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:49:39Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:d484fca2-e55a-4a8f-a40e-3348e3fc29d42022-03-27T08:19:09ZBacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d484fca2-e55a-4a8f-a40e-3348e3fc29d4EnglishSymplectic Elements at Oxford2011Darton, TGuiver, MNaylor, SKaczmarski, EBorrow, RRead, RAmong 384 patients with confirmed meningococcal disease, the likelihood of detecting Neisseria meningitidis DNA in cerebrospinal fluid (CSF) increased with age, serogroup B infection, and prehospitalization antibiotic treatment. Plasma and CSF genomic bacterial loads of non-B N. meningitidis serogroups correlated significantly. Serogroup B-infected patients with genotype TNF2 (-308A) had significantly higher CSF bacterial loads. |
| spellingShingle | Darton, T Guiver, M Naylor, S Kaczmarski, E Borrow, R Read, R Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title | Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title_full | Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title_fullStr | Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title_full_unstemmed | Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title_short | Bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics. |
| title_sort | bacterial genomic detection within cerebrospinal fluid of patients with meningococcal disease is influenced by microbial and host characteristics |
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