Concise and enantioselective synthesis of the aminocyclitol core of hygromycin A.
[reaction: see text] Stereoselective aminohydroxylation and dihydroxylation using osmium(VIII) oxidants enabled the short and efficient synthesis of the aminocyclitol core of hygromycin A. In addition to allowing the selective introduction of the heteroatoms N and O, the use of osmium (via an osmate...
Main Authors: | Donohoe, T, Johnson, P, Pye, R, Keenan, M |
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Format: | Journal article |
Language: | English |
Published: |
2005
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