Computational simulation of the flow dynamic field in a porous ureteric stent

<p>Ureteric stents are employed clinically to manage urinary obstructions or other pathological conditions. Stents made of porous and biodegradable materials have gained increasing interest, because of their excellent biocompatibility and the potential for overcoming the so-called ‘forgotten s...

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Main Authors: Yang, X, Mosayyebi, A, Carugo, D
Format: Journal article
Language:English
Published: Springer 2022
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author Yang, X
Mosayyebi, A
Carugo, D
author_facet Yang, X
Mosayyebi, A
Carugo, D
author_sort Yang, X
collection OXFORD
description <p>Ureteric stents are employed clinically to manage urinary obstructions or other pathological conditions. Stents made of porous and biodegradable materials have gained increasing interest, because of their excellent biocompatibility and the potential for overcoming the so-called ‘forgotten stent syndrome’. However, there is very limited characterisation of their flow dynamic performance. In this study, a CFD model of the occluded and unoccluded urinary tract was developed to investigate the urinary flow dynamics in the presence of a porous ureteric stent. With increasing the permeability of the porous material (i.e., from 10<sup>−18</sup> to 10<sup>−10</sup> m<sup>2</sup>) both the total mass flow rate through the ureter and the average fluid velocity within the stent increased. In the unoccluded ureter, the total mass flow rate increased of 7.7% when a porous stent with permeability of 10<sup>−10</sup> m<sup>2</sup> was employed instead of an unporous stent. Drainage performance further improved in the presence of a ureteral occlusion, with the porous stent resulting in 10.2% greater mass flow rate compared to the unporous stent. Findings from this study provide fundamental insights into the flow performance of porous ureteric stents, with potential utility in the development pipeline of these medical devices.</p>
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spelling oxford-uuid:d4b84347-2619-4177-b63d-10156f89fd232023-08-18T11:32:54ZComputational simulation of the flow dynamic field in a porous ureteric stentJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d4b84347-2619-4177-b63d-10156f89fd23EnglishSymplectic ElementsSpringer 2022Yang, XMosayyebi, ACarugo, D<p>Ureteric stents are employed clinically to manage urinary obstructions or other pathological conditions. Stents made of porous and biodegradable materials have gained increasing interest, because of their excellent biocompatibility and the potential for overcoming the so-called ‘forgotten stent syndrome’. However, there is very limited characterisation of their flow dynamic performance. In this study, a CFD model of the occluded and unoccluded urinary tract was developed to investigate the urinary flow dynamics in the presence of a porous ureteric stent. With increasing the permeability of the porous material (i.e., from 10<sup>−18</sup> to 10<sup>−10</sup> m<sup>2</sup>) both the total mass flow rate through the ureter and the average fluid velocity within the stent increased. In the unoccluded ureter, the total mass flow rate increased of 7.7% when a porous stent with permeability of 10<sup>−10</sup> m<sup>2</sup> was employed instead of an unporous stent. Drainage performance further improved in the presence of a ureteral occlusion, with the porous stent resulting in 10.2% greater mass flow rate compared to the unporous stent. Findings from this study provide fundamental insights into the flow performance of porous ureteric stents, with potential utility in the development pipeline of these medical devices.</p>
spellingShingle Yang, X
Mosayyebi, A
Carugo, D
Computational simulation of the flow dynamic field in a porous ureteric stent
title Computational simulation of the flow dynamic field in a porous ureteric stent
title_full Computational simulation of the flow dynamic field in a porous ureteric stent
title_fullStr Computational simulation of the flow dynamic field in a porous ureteric stent
title_full_unstemmed Computational simulation of the flow dynamic field in a porous ureteric stent
title_short Computational simulation of the flow dynamic field in a porous ureteric stent
title_sort computational simulation of the flow dynamic field in a porous ureteric stent
work_keys_str_mv AT yangx computationalsimulationoftheflowdynamicfieldinaporousuretericstent
AT mosayyebia computationalsimulationoftheflowdynamicfieldinaporousuretericstent
AT carugod computationalsimulationoftheflowdynamicfieldinaporousuretericstent